9/23/2023 0 Comments Oxford big read![]() ![]() Consequently, the SNP effect sizes refer to the change in phenotype (quantitative traits) or log-odds (binary traits) corresponding to possession of an additional copy of the ALT allele.Ī full interpretation, or comparison with other studies, also requires knowledge of any transformations performed on the phenotypes which are described in the references cited above. In all studies, the effect allele is the ALT allele. The browser also provides effect sizes and standard errors for each SNP tested against each phenotype. ![]() So for example, at this SNP the REF allele is T and the ALT allele is C. Prof Stephen Smith, FMRIB, Wellcome Centre for Integrative Neuroimaging, University of OxfordĪllele coding, SNP effect sizes and p-valuesįor each SNP two alleles are reported with two alleles REF and ALT. Prof Jonathan Marchini, Department of Statistics, University of Oxford The genetic data and brain imaging data underlying this study are described in the following papers Association analysis was carried out using BGENIE and is described in full in this paper: Elliott, L. The primary source is results from 3,143 GWAS of Brain Imaging Derived Phenotypes (IDPs) measured on 9,707 participants of the UK Biobank study. ![]() This is a copy of the data from BIGv2, originally hosted atĪccess the updated and expanded data from BIG40, Legacy copy of original Oxford Brain Imaging Genetics Server ![]()
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